Assay Detail
Binding
CHEMBL4014609
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at FXR (unknown origin) assessed as recruitment of SRC1 peptide to FXR by FRET assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.03 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL566315 | OBETICHOLIC ACID | 4.0 | 1 | 7.00 |
| CHEMBL240597 | CHENODIOL | 4.0 | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL566315 | OBETICHOLIC ACID | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL240597 | CHENODIOL | EC50 | = | 9000.0 | nM | 5.05 |