Assay Detail
Functional
CHEMBL4014669
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Antibiofilm activity against Escherichia coli MTCC 739 after 24 hrs by crystal violet staining based method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel pyrazolo[3,4-b]quinolinyl acetamide analogs, their evaluation for antimicrobial and anticancer activities, validation by molecular modeling and CoMFA analysis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.74 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8 | CIPROFLOXACIN | 4.0 | 1 | 6.10 |
| CHEMBL4077877 | — | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8 | CIPROFLOXACIN | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL4077877 | — | IC50 | = | 4200.0 | nM | 5.38 |