Assay Detail
Functional
CHEMBL4016674
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse NMUR1 expressed in HEK293 cells assessed as induction of calcium mobilization after 18 hrs by Fluo-4 AM dye based FLIPR assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Human Neuromedin U Receptor 1-Selective Hexapeptide Agonist with Enhanced Serum Stability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.72 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4097923 | — | — | 1 | 9.38 |
| CHEMBL4105671 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4097923 | — | EC50 | = | 0.42 | nM | 9.38 |
| CHEMBL4105671 | — | EC50 | = | 8.9 | nM | 8.05 |