Assay Detail
ADMET
CHEMBL4017950
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Growth inhibition of HEK293 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.36 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL469912 | PUROMYCIN | 2.0 | 1 | 6.40 |
| CHEMBL35228 | PYRONARIDINE | 3.0 | 1 | 5.28 |
| CHEMBL4101406 | — | — | 1 | 4.94 |
| CHEMBL4059982 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL469912 | PUROMYCIN | IC50 | = | 399.0 | nM | 6.40 |
| CHEMBL35228 | PYRONARIDINE | IC50 | = | 5220.0 | nM | 5.28 |
| CHEMBL4101406 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL4059982 | — | IC50 | = | 15900.0 | nM | 4.80 |