Assay Detail
ADMET
CHEMBL4018051
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human meprin alpha expressed in S2 insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
First insight into structure-activity relationships of selective meprin β inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.02 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4078433 | — | — | 1 | 5.48 |
| CHEMBL4105563 | — | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4078433 | — | IC50 | = | 3290.0 | nM | 5.48 |
| CHEMBL4105563 | — | IC50 | = | 27350.0 | nM | 4.56 |