Assay Detail
Binding
CHEMBL4021136
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Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 30 min followed by substrate addition measured every 2 secs for 50 secs by Ellman's method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Stereospecific cholinesterase inhibition by O,S-diethylphenylphosphonothioate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.02 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2179375 | — | — | 1 | 5.52 |
| CHEMBL592433 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2179375 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL592433 | — | IC50 | = | 30000.0 | nM | 4.52 |