Assay Detail
ADMET
CHEMBL4024189
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Antiproliferative activity against human BJ cells after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | BJ |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and Biological Evaluation of Selenium-Containing 4-Anilinoquinazoline Derivatives as Novel Antimitotic Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.69 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL492399 | VERUBULIN | 2.0 | 1 | 7.82 |
| CHEMBL4096662 | — | — | 1 | 7.72 |
| CHEMBL4076686 | — | — | 1 | 7.72 |
| CHEMBL4073184 | — | — | 1 | 7.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL492399 | VERUBULIN | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL4096662 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL4076686 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL4073184 | — | IC50 | = | 33.0 | nM | 7.48 |