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Assay Detail

CHEMBL4028442

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Binding
Inhibition of PRAS40 binding to human GST-tagged 14-3-3 protein zeta/delta expressed in Escherichia coli BL21(DE3) by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

14-3-3 protein zeta/delta (CHEMBL4105899)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

X-ray Structures of Target-Ligand Complexes Containing Compounds with Assay Interference Potential.
Gilberg E, Gütschow M, Bajorath J.
J Med Chem (2018) 61 : 1276 -1284
PubMed 29328660 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.03 5.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL119235 1 5.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL119235 IC50 = 9300.0 nM 5.03