Assay Detail
ADMET
CHEMBL4031609
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Cytotoxicity against CHO-MG cells assessed as reduction in cell viability after 48 hrs in presence of aminoguanidine by MTS assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO-MG |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and Bioevaluation of Macrocycle-Polyamine Conjugates as Cell Migration Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.43 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4092941 | — | — | 1 | 5.62 |
| CHEMBL4077417 | — | — | 1 | 5.59 |
| CHEMBL4077239 | — | — | 1 | 5.58 |
| CHEMBL4065836 | — | — | 1 | 5.55 |
| CHEMBL4093452 | — | — | 1 | 5.53 |
| CHEMBL4065277 | — | — | 1 | 5.22 |
| CHEMBL4074949 | — | — | 1 | 4.95 |
| CHEMBL4095381 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4092941 | — | IC50 | = | 2370.0 | nM | 5.62 |
| CHEMBL4077417 | — | IC50 | = | 2550.0 | nM | 5.59 |
| CHEMBL4077239 | — | IC50 | = | 2620.0 | nM | 5.58 |
| CHEMBL4065836 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL4093452 | — | IC50 | = | 2960.0 | nM | 5.53 |
| CHEMBL4065277 | — | IC50 | = | 5950.0 | nM | 5.22 |
| CHEMBL4074949 | — | IC50 | = | 11330.0 | nM | 4.95 |
| CHEMBL4095381 | — | IC50 | > | 100000.0 | nM | - |