Assay Detail
Functional
CHEMBL4033804
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Cytotoxicity against human Kasumi-1 cells incubated for 48 hrs by MTS assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Kasumi 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.09 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL555196 | SILVESTROL | — | 1 | 7.62 |
| CHEMBL449686 | STREBLOSIDE | — | 1 | 7.07 |
| CHEMBL1751 | DIGOXIN | 4.0 | 1 | 7.03 |
| CHEMBL400876 | — | — | 1 | 7.01 |
| CHEMBL4100694 | — | — | 1 | 6.74 |
| CHEMBL4073120 | — | — | 1 | - |
| CHEMBL4073923 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL555196 | SILVESTROL | IC50 | = | 24.0 | nM | 7.62 |
| CHEMBL449686 | STREBLOSIDE | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL1751 | DIGOXIN | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL400876 | — | IC50 | = | 97.0 | nM | 7.01 |
| CHEMBL4100694 | — | IC50 | = | 181.0 | nM | 6.74 |
| CHEMBL4073120 | — | IC50 | - | — | - | |
| CHEMBL4073923 | — | IC50 | - | — | - |