Assay Detail
Binding
CHEMBL4035332
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Inhibition of CYP1B1 (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of cytochrome P450 (CYP) 1B1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.74 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243664 | ACACETIN | — | 1 | 8.15 |
| CHEMBL117 | CHRYSIN | — | 1 | 7.80 |
| CHEMBL90568 | DIOSMETIN | — | 1 | 7.80 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 7.64 |
| CHEMBL164 | MYRICETIN | — | 1 | 7.57 |
| CHEMBL487402 | EUPATORIN | — | 1 | 7.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243664 | ACACETIN | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL117 | CHRYSIN | Ki | = | 16.0 | nM | 7.80 |
| CHEMBL90568 | DIOSMETIN | Ki | = | 16.0 | nM | 7.80 |
| CHEMBL50 | QUERCETIN | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL164 | MYRICETIN | Ki | = | 27.0 | nM | 7.57 |
| CHEMBL487402 | EUPATORIN | Ki | = | 35.0 | nM | 7.46 |