Assay Detail
Binding
CHEMBL4035333
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP1B1 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5 mins by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Liver |
| Subcellular | Microsomes |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of cytochrome P450 (CYP) 1B1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.62 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL490170 | HOMOERIODICTYOL | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL490170 | HOMOERIODICTYOL | IC50 | = | 240.0 | nM | 6.62 |