Assay Detail
Binding
CHEMBL4035346
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CYP1B1 expressed in Escherichia coli
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of cytochrome P450 (CYP) 1B1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.10 | 7.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL85139 | RUTAECARPINE | — | 1 | 7.26 |
| CHEMBL85826 | — | — | 1 | 7.08 |
| CHEMBL312149 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL85139 | RUTAECARPINE | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL85826 | — | IC50 | = | 84.0 | nM | 7.08 |
| CHEMBL312149 | — | IC50 | = | 110.0 | nM | 6.96 |