Assay Detail
Functional
CHEMBL4035955
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.14 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL371562 | — | — | 1 | 5.42 |
| CHEMBL2437372 | — | — | 1 | 5.06 |
| CHEMBL1779057 | LICOCHALCONE E | — | 1 | 5.04 |
| CHEMBL2437370 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL371562 | — | IC50 | = | 3830.0 | nM | 5.42 |
| CHEMBL2437372 | — | IC50 | = | 8780.0 | nM | 5.06 |
| CHEMBL1779057 | LICOCHALCONE E | IC50 | = | 9090.0 | nM | 5.04 |
| CHEMBL2437370 | — | IC50 | = | 9350.0 | nM | 5.03 |