Assay Detail
Binding
CHEMBL4035964
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 15 mins followed by substrate addition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.57 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL480477 | GLABRIDIN | — | 1 | 7.00 |
| CHEMBL1864439 | — | — | 1 | 6.60 |
| CHEMBL4069449 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL480477 | GLABRIDIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1864439 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL4069449 | — | IC50 | = | 800.0 | nM | 6.10 |