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Assay Detail

CHEMBL4037088

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human erythrocyte AChE
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
Talele TT.
J Med Chem (2018) 61 : 2166 -2210
PubMed 28850227 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL283509 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL283509 IC50 = 1.0 nM 9.00