Assay Detail
Binding
CHEMBL4037098
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at RXRbeta (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.45 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1023 | BEXAROTENE | 4.0 | 1 | 7.62 |
| CHEMBL108402 | — | — | 1 | 6.11 |
| CHEMBL107039 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1023 | BEXAROTENE | EC50 | = | 24.0 | nM | 7.62 |
| CHEMBL108402 | — | EC50 | = | 770.0 | nM | 6.11 |
| CHEMBL107039 | — | EC50 | = | 2400.0 | nM | 5.62 |