Assay Detail
Binding
CHEMBL4037102
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to 5-HT1A (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.91 | 8.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL49 | BUSPIRONE | 4.0 | 1 | 8.32 |
| CHEMBL284092 | GEPIRONE | 4.0 | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL49 | BUSPIRONE | Ki | = | 4.78 | nM | 8.32 |
| CHEMBL284092 | GEPIRONE | Ki | = | 31.8 | nM | 7.50 |