Assay Detail
Functional
CHEMBL4037118
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma brucei brucei after 72 hrs by resazurin-based fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.50 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2441392 | — | — | 1 | 6.75 |
| CHEMBL2347704 | ACOZIBOROLE | 2.0 | 1 | 6.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2441392 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL2347704 | ACOZIBOROLE | IC50 | = | 556.0 | nM | 6.25 |