Assay Detail
Binding
CHEMBL4037120
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human plasma thrombin using chromogenix AB as substrate after 30 secs by UV-spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.44 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4083414 | — | — | 1 | 7.52 |
| CHEMBL4091198 | — | — | 1 | 7.40 |
| CHEMBL1166 | ARGATROBAN | 4.0 | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4083414 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL4091198 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL1166 | ARGATROBAN | Ki | = | 40.0 | nM | 7.40 |