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Assay Detail

CHEMBL4037302

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV-1 subtype C by p24 ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Inhibitors of HIV-1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir.
Meanwell NA, Krystal MR, Nowicka-Sans B, Langley DR, Conlon DA, Eastgate MD, Grasela DM, Timmins P, Wang T, Kadow JF.
J Med Chem (2018) 61 : 62 -80
PubMed 29271653 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.94 8.94

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3301620 TEMSAVIR 2.0 1 8.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3301620 TEMSAVIR EC50 = 1.14 nM 8.94