Assay Detail
ADMET
CHEMBL4038378
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Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiprotozoal Activity-Based Profiling of a Dichloromethane Extract from Anthemis nobilis Flowers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 5.51 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | 4.0 | 1 | 7.80 |
| CHEMBL4070082 | — | — | 1 | 5.82 |
| CHEMBL4075374 | — | — | 1 | 5.75 |
| CHEMBL4059870 | — | — | 1 | 5.75 |
| CHEMBL4103119 | — | — | 1 | 5.31 |
| CHEMBL4068842 | — | — | 1 | 5.29 |
| CHEMBL4076244 | — | — | 1 | 5.29 |
| CHEMBL4076328 | — | — | 1 | 5.29 |
| CHEMBL4070737 | — | — | 1 | 5.28 |
| CHEMBL4076872 | — | — | 1 | 5.28 |
| CHEMBL4101872 | — | — | 1 | 5.28 |
| CHEMBL4094141 | — | — | 1 | 5.24 |
| CHEMBL4080773 | — | — | 1 | 5.14 |
| CHEMBL4076635 | — | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL4070082 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL4075374 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL4059870 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL4103119 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL4068842 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL4076244 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL4076328 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL4070737 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL4076872 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL4101872 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL4094141 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL4080773 | — | IC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL4076635 | — | IC50 | = | 28200.0 | nM | 4.55 |