Assay Detail
Binding
CHEMBL4038414
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human BAZ2A (M1792 to L1905 residues) expressed in bacterial expression system by BROMOscan assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Bromodomain adjacent to zinc finger domain protein 2A (CHEMBL3108642) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Methylpyrrole inhibitors of BET bromodomains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.00 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4063051 | — | — | 1 | 5.00 |
| CHEMBL4088466 | — | — | 1 | 5.00 |
| CHEMBL3786012 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4063051 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4088466 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL3786012 | — | IC50 | > | 10000.0 | nM | - |