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Target Snapshot

CHEMBL3108642 Target Snapshot

Bromodomain adjacent to zinc finger domain protein 2A · SINGLE PROTEIN · Homo sapiens

220Compounds
87Assays
0Approved Drugs
181.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9UIF9. Use UniProt Q9UIF9 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9UIF9 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Bromodomain adjacent to zinc finger domain protein 2A as ChEMBL target CHEMBL3108642, mapped to UniProt Q9UIF9. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Bromodomain adjacent to zinc finger domain protein 2A
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3108642
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9UIF9
Bromodomain adjacent to zinc finger domain protein 2A
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Bromodomain adjacent to zinc finger domain protein 2A is the right protein anchor across sources, using UniProt Q9UIF9 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelBromodomain adjacent to zinc finger domain protein 2A
UniProt AccessionQ9UIF9
Component TypeProtein
Sequence Length1905 aa

Bromodomain adjacent to zinc finger domain protein 2A

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Bromodomain adjacent to zinc finger domain protein 2A, mapped to UniProt Q9UIF9. Sequence length is 1905 aa.

Mapped IDQ9UIF9
Review nameBromodomain adjacent to zinc finger domain protein 2A
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

IC50137.0
EC501.0
KD43.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4449894 7.8 Kd 15.85 Preclinical
CHEMBL3739699 7.22 Kd 60.0 Preclinical
CHEMBL4296718 6.96 Kd 109.0 Preclinical
CHEMBL4296718 6.89 IC50 130.0 Preclinical
CHEMBL5274024 6.85 Kd 140.0 Preclinical
CHEMBL3770199 6.8 IC50 160.0 Preclinical
CHEMBL4456922 6.5 IC50 316.23 Preclinical
CHEMBL3739699 6.4 IC50 400.0 Preclinical
CHEMBL3415185 6.35 IC50 450.0 Preclinical
CHEMBL4466159 6.3 IC50 501.19 Preclinical
Distribution

pChEMBL Value Distribution

21
5.0
22
5.5
18
6.0
12
6.5
1
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

87
Total Assays
106
Tested Compounds
1
Assay Types
Binding — 87 assays, 106 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 41 75 4.9
assay format 33 29 5.8
cell-based format 13 2 5.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine