Assay Detail
Binding
CHEMBL4039191
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Inhibition of human dopamine D4.2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Return of D4 Dopamine Receptor Antagonists in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.27 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4068924 | — | — | 1 | 8.44 |
| CHEMBL103772 | — | — | 1 | 8.38 |
| CHEMBL69759 | SONEPIPRAZOLE | 2.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4068924 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL103772 | — | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL69759 | SONEPIPRAZOLE | Ki | = | 10.1 | nM | 8.00 |