Assay Detail
Functional
CHEMBL4040222
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-2 infected in human MT4 cells measured on day 5 post-infection by trypan blue dye staining-based method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 2 (CHEMBL380) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 2 |
Publication
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.25 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1766281 | — | — | 1 | 5.34 |
| CHEMBL4073268 | — | — | 1 | 5.30 |
| CHEMBL519667 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1766281 | — | EC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL4073268 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL519667 | — | EC50 | = | 8000.0 | nM | 5.10 |