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Assay Detail

CHEMBL4042876

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Functional
Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D10 infected in erythrocytes after 48 hrs by giemsa staining based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents.
Espinoza-Moraga M, Singh K, Njoroge M, Kaur G, Okombo J, De Kock C, Smith PJ, Wittlin S, Chibale K.
Bioorg Med Chem Lett (2017) 27 : 658 -661
PubMed 28012840 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL374975 FUSIDIC ACID 3.0 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL374975 FUSIDIC ACID IC50 = 50000.0 nM 4.30