Assay Detail
Functional
CHEMBL4043431
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MX1 cells after 72 hrs by CellTiter-Glo assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MX1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Drug Discovery Targeting Bromodomain-Containing Protein 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.33 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4075567 | — | — | 1 | 8.24 |
| CHEMBL4105618 | — | — | 1 | 8.06 |
| CHEMBL3906306 | — | — | 1 | 6.63 |
| CHEMBL3962469 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4075567 | — | EC50 | = | 5.7 | nM | 8.24 |
| CHEMBL4105618 | — | EC50 | = | 8.7 | nM | 8.06 |
| CHEMBL3906306 | — | EC50 | = | 233.0 | nM | 6.63 |
| CHEMBL3962469 | — | EC50 | = | 398.0 | nM | 6.40 |