Assay Detail
Functional
CHEMBL4043438
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MX1 cells incubated for >= 72 hrs by CellTiter-Glo assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MX1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Drug Discovery Targeting Bromodomain-Containing Protein 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 7.40 | 8.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4088597 | — | — | 1 | 8.03 |
| CHEMBL4096313 | — | — | 1 | 8.00 |
| CHEMBL4078267 | — | — | 1 | 7.85 |
| CHEMBL4067346 | — | — | 1 | 7.80 |
| CHEMBL4104956 | — | — | 1 | 7.32 |
| CHEMBL4075943 | — | — | 1 | 7.01 |
| CHEMBL4063051 | — | — | 1 | 6.80 |
| CHEMBL4075159 | — | — | 1 | 6.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4088597 | — | EC50 | = | 9.4 | nM | 8.03 |
| CHEMBL4096313 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4078267 | — | EC50 | = | 14.0 | nM | 7.85 |
| CHEMBL4067346 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL4104956 | — | EC50 | = | 48.0 | nM | 7.32 |
| CHEMBL4075943 | — | EC50 | = | 97.0 | nM | 7.01 |
| CHEMBL4063051 | — | EC50 | = | 160.0 | nM | 6.80 |
| CHEMBL4075159 | — | EC50 | = | 433.0 | nM | 6.36 |