Assay Detail
Binding
CHEMBL4044711
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rice alpha-glucosidase pre-incubated for 1 hr followed by p-nitrophenyl-alpha-D-glucopyranoside substrate addition by fluorescence detection based assay
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryza sativa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
α-Geminal disubstituted pyrrolidine iminosugars and their C-4-fluoro analogues: Synthesis, glycosidase inhibition and molecular docking studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.30 | 7.30 |
| Ki | 2 | 7.55 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1561 | MIGLITOL | 4.0 | 2 | 7.55 |
| CHEMBL4059852 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1561 | MIGLITOL | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL1561 | MIGLITOL | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL4059852 | — | IC50 | = | 463000.0 | nM | - |
| CHEMBL4059852 | — | Ki | = | 376000.0 | nM | - |