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Assay Detail

CHEMBL4049316

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Ebolavirus Mayinga infected in African green monkey Vero E6 cells after 72 hrs by eGFP assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Ebolavirus
Cell Type Vero C1008
Confidence 1 — Organism
Curated By Autocuration

Target

Ebolavirus (CHEMBL4434621)
Type ORGANISM
Organism Ebolavirus

Publication

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.
Capuzzi SJ, Sun W, Muratov EN, Martínez-Romero C, He S, Zhu W, Li H, Tawa G, Fisher EG, Xu M, Shinn P, Qiu X, García-Sastre A, Zheng W, Tropsha A.
J Med Chem (2018) 61 : 3582 -3594
PubMed 29624387 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL569864 1 6.00
CHEMBL4084475 1 6.00
CHEMBL4064522 1 6.00
CHEMBL399021 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL569864 IC50 = 1000.0 nM 6.00
CHEMBL4084475 IC50 = 1000.0 nM 6.00
CHEMBL4064522 IC50 = 1000.0 nM 6.00
CHEMBL399021 IC50 = 1000.0 nM 6.00