Assay Detail
Functional
CHEMBL4050950
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Antiproliferative activity against human K562/ADR cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562/Adr |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
6-OH-Phenanthroquinolizidine Alkaloid and Its Derivatives Exert Potent Anticancer Activity by Delaying S Phase Progression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.98 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3356793 | — | — | 1 | 8.59 |
| CHEMBL399454 | — | — | 1 | 6.86 |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3356793 | — | IC50 | = | 2.6 | nM | 8.59 |
| CHEMBL399454 | — | IC50 | = | 137.5 | nM | 6.86 |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 3310.2 | nM | 5.48 |