Assay Detail
Functional
CHEMBL4053552
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human HCT116 cells after 96 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.13 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL256279 | BENGAMIDE A | — | 1 | 9.40 |
| CHEMBL4061080 | — | — | 1 | 9.10 |
| CHEMBL376628 | BENGAMIDE E | — | 1 | 8.42 |
| CHEMBL4078211 | — | — | 1 | 7.64 |
| CHEMBL4075346 | — | — | 1 | 7.36 |
| CHEMBL4089242 | — | — | 1 | 6.85 |
| CHEMBL4102603 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL256279 | BENGAMIDE A | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL4061080 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL376628 | BENGAMIDE E | IC50 | = | 3.8 | nM | 8.42 |
| CHEMBL4078211 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL4075346 | — | IC50 | = | 44.0 | nM | 7.36 |
| CHEMBL4089242 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL4102603 | — | IC50 | > | 50000.0 | nM | - |