Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4057022

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 12 hrs by Griess assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type RAW264.7
Confidence 1 — Organism
Curated By Autocuration

Target

RAW264.7 (CHEMBL612557)
Type CELL-LINE
Organism Mus musculus

Publication

Flavonoid glycosides from Barringtonia acutangula.
Vien LT, Van QTT, Hanh TTH, Huong PTT, Thuy NTK, Cuong NT, Dang NH, Thanh NV, Cuong NX, Nam NH, Kiem PV, Minh CV.
Bioorg Med Chem Lett (2017) 27 : 3776 -3781
PubMed 28688956 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL378104 CARDAMOMIN 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL378104 CARDAMOMIN IC50 = 2200.0 nM 5.66