Assay Detail
Binding
CHEMBL4059044
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human full length recombinant HuR expressed in Escherichia coli Rosetta DH5alpha measured for 30 mins by DMR analysis
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.35 | 5.35 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4075458 | — | — | 2 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4075458 | — | Kd | = | 4500.0 | nM | 5.35 |
| CHEMBL4075458 | — | Activity | - | — | - |