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Target Snapshot

CHEMBL1250379 Target Snapshot

ELAV-like protein 1 · SINGLE PROTEIN · Homo sapiens

65Compounds
54Assays
0Approved Drugs
77.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q15717. Use UniProt Q15717 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q15717 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats ELAV-like protein 1 as ChEMBL target CHEMBL1250379, mapped to UniProt Q15717. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
ELAV-like protein 1
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL1250379
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q15717
ELAV-like protein 1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether ELAV-like protein 1 is the right protein anchor across sources, using UniProt Q15717 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelELAV-like protein 1
UniProt AccessionQ15717
Component TypeProtein
Sequence Length326 aa

ELAV-like protein 1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as ELAV-like protein 1, mapped to UniProt Q15717. Sequence length is 326 aa.

Mapped IDQ15717
Review nameELAV-like protein 1
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

IC5033.0
KI29.0
KD15.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1242196 11.0 Kd 0.01 Preclinical
CHEMBL1240928 10.0 Kd 0.1 Preclinical
CHEMBL3752910 7.97 Kd 10.69 Preclinical
CHEMBL4075458 7.89 Ki 12.8 Preclinical
CHEMBL4064932 7.82 Ki 15.0 Preclinical
CHEMBL4095060 7.39 Ki 41.0 Preclinical
CHEMBL4100171 7.32 Ki 48.0 Preclinical
CHEMBL227075 7.3 Ki 50.0 Preclinical
CHEMBL4105230 7.26 Ki 55.0 Preclinical
CHEMBL4073526 7.25 Ki 56.0 Preclinical
Distribution

pChEMBL Value Distribution

14
5.0
4
5.5
6
6.0
2
6.5
9
7.0
4
7.5
3
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

54
Total Assays
27
Tested Compounds
2
Assay Types
Binding — 53 assays, 27 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 36 19 6.2
cell-based format 12 0
assay format 5 8 7.2
Functional — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine