Compound Detail
CHEMBL1242196
DEHYDROMUTACTIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1242196 |
| Name | DEHYDROMUTACTIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MQXUOBANQWOATN-UHFFFAOYSA-N |
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
284.3
MW (Da)
2.89
ALogP
5
HBA
3
HBD
90.9
PSA (Ų)
0.64
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 5 meas. best 11.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| ELAV-like protein 1 CHEMBL1250379 | Kd | 11.0 | 9.064 | 0.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| ELAV-like protein 1 | Kd | = | 0.01 | nM | 11.0 | Inhibition of recombinant full length HuR assessed as protein dimerization with ... | 17632515 |
| ELAV-like protein 1 | Kd | = | 0.1 | nM | 10.0 | Inhibition of recombinant full length HuR assessed as protein dimerization with ... | 17632515 |
| ELAV-like protein 1 | Kd | = | 6.0 | nM | 8.22 | Binding affinity to recombinant full length HuR assessed as protein dimerization... | 17632515 |
| ELAV-like protein 1 | Kd | = | 9.0 | nM | 8.05 | Inhibition of recombinant full length HuR assessed as protein interaction with T... | 17632515 |
| ELAV-like protein 1 | Kd | = | 9.0 | nM | 8.05 | Inhibition of recombinant full length HuR assessed as protein interaction with T... | 17632515 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17632515 | 10.1038/nchembio.2007.14 | ELAV-like protein 1 | 9 |
| 17632515 | 10.1038/nchembio.2007.14 | Monocyte | 7 |
| 17632515 | 10.1038/nchembio.2007.14 | PBMC | 2 |
Data from ChEMBL 36 via Core Engine