Assay Detail
Binding
CHEMBL4120902
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Binding affinity to recombinant HMGB1 box A (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
High Mobility Group Box-1 (HMGb1): Current Wisdom and Advancement as a Potential Drug Target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.42 | 8.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4129393 | — | — | 1 | 8.83 |
| CHEMBL424 | SALICYLIC ACID | 3.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4129393 | — | Kd | = | 1.48 | nM | 8.83 |
| CHEMBL424 | SALICYLIC ACID | Kd | = | 1000.0 | nM | 6.00 |