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Assay Detail

CHEMBL4121506

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]Tyr11-somatostatin-14 from mouse SST receptor after 60 mins by scintillation counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 5 — Multiple protein complex / RNA
Curated By Intermediate

Target

Somatostatin receptor (CHEMBL2111427)
Type PROTEIN FAMILY
Organism Mus musculus

Publication

Identification and biological evaluation of thiazole-based inverse agonists of RORγt.
Gege C, Cummings MD, Albers M, Kinzel O, Kleymann G, Schlüter T, Steeneck C, Nelen MI, Milligan C, Spurlino J, Xue X, Leonard K, Edwards JP, Fourie A, Goldberg SD, Hoffmann T.
Bioorg Med Chem Lett (2018) 28 : 1446 -1455
PubMed 29631962 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.51 9.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4128926 1 9.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4128926 IC50 = 0.31 nM 9.51