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Target Snapshot

CHEMBL2111427 Target Snapshot

Somatostatin receptor · PROTEIN FAMILY · Mus musculus

39Compounds
21Assays
0Approved Drugs
21.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P30935. Use UniProt P30935 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P30935 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Somatostatin receptor as ChEMBL target CHEMBL2111427, mapped to UniProt P30935. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Somatostatin receptor
PROTEIN FAMILY · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL2111427
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P30935
Somatostatin receptor type 3
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Somatostatin receptor is the right protein anchor across sources, using UniProt P30935 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSomatostatin receptor type 3
UniProt AccessionP30935
Component TypeProtein
Sequence Length428 aa

Somatostatin receptor type 3

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Somatostatin receptor, mapped to UniProt P30935. ChEMBL maps the protein component as Somatostatin receptor type 3. Sequence length is 428 aa.

Mapped IDP30935
Review nameSomatostatin receptor
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

IC5020.0
KD1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1823872 10.13 IC50 0.074 Clinical
CHEMBL4128926 9.51 IC50 0.31 Preclinical
CHEMBL437814 8.25 Kd 5.57 Preclinical
CHEMBL28824 5.39 IC50 4100.0 Preclinical
CHEMBL282618 5.3 IC50 5000.0 Preclinical
CHEMBL29752 5.29 IC50 5100.0 Preclinical
CHEMBL28852 5.25 IC50 5600.0 Preclinical
CHEMBL29102 5.23 IC50 5900.0 Preclinical
CHEMBL282802 5.16 IC50 7000.0 Preclinical
CHEMBL29311 5.1 IC50 8000.0 Preclinical
Distribution

pChEMBL Value Distribution

8
5.0
1
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
1
9.5
pChEMBL
Assay Landscape

Assay Landscape

21
Total Assays
15
Tested Compounds
1
Assay Types
Binding — 21 assays, 15 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 11 14 5.6
protein format 10 1 9.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine