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Compound Detail

CHEMBL437814

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C[C@H](O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)[C@@H](C)O

Basic Information

ChEMBL ID CHEMBL437814
Phase Preclinical
Structure Type MOL
InChI Key IHEYIQXRXFGYBM-VJRYJWGJSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

1396.6
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C63H89N13O19S2
MW 1396.61

Activity Summary

Kd 1 meas. best 8.25

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Somatostatin receptor
CHEMBL2111427
Kd 8.25 8.25 5.6 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
7966134 10.1021/jm00048a011 Somatostatin receptor 1

Data from ChEMBL 36 via Core Engine