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Assay Detail

CHEMBL806572

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Dissociation constant binding to somatostatin receptor of At-20 mouse pituitary carcinoma cell membranes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type Pituitary gland cell
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Somatostatin receptor (CHEMBL2111427)
Type PROTEIN FAMILY
Organism Mus musculus

Publication

Generally applicable, convenient solid-phase synthesis and receptor affinities of octreotide analogs.
Edwards WB, Fields CG, Anderson CJ, Pajeau TS, Welch MJ, Fields GB.
J Med Chem (1994) 37 : 3749 -3757
PubMed 7966134 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.25 8.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL437814 1 8.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL437814 Kd = 5.57 nM 8.25