Assay Detail
Binding
CHEMBL4123966
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]IMPY from fibrillar amyloid beta 42 (unknown origin) after 3 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Isoxazole-tethered diarylheptanoid analogs: Discovery of a new drug-like PAR2 antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.86 | 6.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL181529 | — | — | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL181529 | — | IC50 | = | 138.0 | nM | 6.86 |