Assay Detail
Functional
CHEMBL4124124
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Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.35 | 6.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1941052 | — | — | 1 | 6.06 |
| CHEMBL4126250 | — | — | 1 | 5.88 |
| CHEMBL4128206 | — | — | 1 | 5.29 |
| CHEMBL4128056 | — | — | 1 | 5.21 |
| CHEMBL4127843 | — | — | 1 | 5.11 |
| CHEMBL4129436 | — | — | 1 | 4.57 |
| CHEMBL1941050 | — | — | 1 | - |
| CHEMBL3360305 | — | — | 1 | - |
| CHEMBL3900791 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1941052 | — | IC50 | = | 870.0 | nM | 6.06 |
| CHEMBL4126250 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL4128206 | — | IC50 | = | 5120.0 | nM | 5.29 |
| CHEMBL4128056 | — | IC50 | = | 6170.0 | nM | 5.21 |
| CHEMBL4127843 | — | IC50 | = | 7860.0 | nM | 5.11 |
| CHEMBL4129436 | — | IC50 | = | 26700.0 | nM | 4.57 |
| CHEMBL1941050 | — | IC50 | - | — | - | |
| CHEMBL3360305 | — | IC50 | - | — | - | |
| CHEMBL3900791 | — | IC50 | - | — | - |