Assay Detail
Binding
CHEMBL4125431
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Competitive inhibition of recombinant human MAO-A using kynuramine as substrate by Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.62 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13045 | CHELERYTHRINE | — | 1 | 6.66 |
| CHEMBL275224 | NORHARMANE | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13045 | CHELERYTHRINE | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL275224 | NORHARMANE | Ki | = | 260.0 | nM | 6.58 |