Assay Detail
Binding
CHEMBL4125657
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Inhibition of soybean lipoxygenase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Glycine max |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.82 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4127281 | — | — | 1 | 5.20 |
| CHEMBL4126039 | — | — | 1 | 4.70 |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4127281 | — | IC50 | = | 6250.0 | nM | 5.20 |
| CHEMBL4126039 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | IC50 | = | 28000.0 | nM | 4.55 |