Assay Detail
Functional
CHEMBL4134726
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Cytotoxicity in human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of naphthazarin derivatives and identification of novel thioredoxin reductase inhibitor as potential anticancer agent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.09 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11475 | — | — | 1 | 6.14 |
| CHEMBL274056 | NAPHTHAZALIN | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11475 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL274056 | NAPHTHAZALIN | IC50 | = | 930.0 | nM | 6.03 |