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Assay Detail

CHEMBL4135401

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Functional
Thrombolytic activity in human blood after 2 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Blood
Confidence 1 — Organism
Curated By Intermediate

Target

Blood (CHEMBL613416)
Type TISSUE
Organism Homo sapiens

Publication

Therapeutic investigations of novel indoxyl-based indolines: A drug target validation and Structure-Activity Relationship of angiotensin-converting enzyme inhibitors with cardiovascular regulation and thrombolytic potential.
Manikandan A, Moharil P, Sathishkumar M, Muñoz-Garay C, Sivakumar A.
Eur J Med Chem (2017) 141 : 417 -426
PubMed 29032034 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.46 7.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4174467 1 7.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4174467 IC50 = 35.0 nM 7.46