Assay Detail
Functional
CHEMBL4135474
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Antichlamydial activity against Chlamydia pneumoniae K7 infected in HL cells after 70 hrs by fluorescent microscopic analysis
8
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlamydia pneumoniae |
| Cell Type | HL |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.74 | 6.51 |
| MIC90 | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL866 | MYCOPHENOLIC ACID | 4.0 | 2 | 6.51 |
| CHEMBL186779 | JERVINE | — | 1 | 4.59 |
| CHEMBL2165578 | PEGANOLE | — | 1 | 4.46 |
| CHEMBL4162501 | — | — | 1 | 4.45 |
| CHEMBL4170050 | — | — | 1 | 4.28 |
| CHEMBL1232979 | — | — | 1 | 4.17 |
| CHEMBL4 | OFLOXACIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL866 | MYCOPHENOLIC ACID | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL186779 | JERVINE | IC50 | = | 25600.0 | nM | 4.59 |
| CHEMBL2165578 | PEGANOLE | IC50 | = | 35100.0 | nM | 4.46 |
| CHEMBL4162501 | — | IC50 | = | 35500.0 | nM | 4.45 |
| CHEMBL4170050 | — | IC50 | = | 52600.0 | nM | 4.28 |
| CHEMBL1232979 | — | IC50 | = | 67200.0 | nM | 4.17 |
| CHEMBL4 | OFLOXACIN | MIC90 | = | 1380.0 | nM | - |
| CHEMBL866 | MYCOPHENOLIC ACID | MIC90 | = | 1000.0 | nM | - |