Assay Detail
Binding
CHEMBL4137421
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Binding affinity to human HSC70 after 2 hrs by fluorescence shift assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Heat shock cognate 71 kDa protein (CHEMBL1275223) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.18 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4168736 | — | — | 1 | 6.18 |
| CHEMBL4165078 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4168736 | — | Kd | = | 660.0 | nM | 6.18 |
| CHEMBL4165078 | — | Kd | > | 10000.0 | nM | - |